Liverpool striker Alexander Isak is expected to be sidelined for at least a couple of months after breaking his leg and undergoing surgery.
Chelsea won for the first time in six Premier League matches when they beat relegation-threatened Wolverhampton Wanderers 3-1 at home on Monday.
Non-league Macclesfield produced perhaps the FA Cup's greatest upset on Saturday when they beat holders Crystal Palace 2-1 in a thirdround thriller, knocking Oliver Glasner's team out of the competition and sending the Moss Rose crowd into raptures.
'I don't think that's fair, because we have other competitions as well we have to try to accommodate.'
IMAGES from Premier League matches played on Saturday
Manchester City maintained their squeeze on Arsenal at the top of the Premier League with a 3-0 victory at Crystal Palace on Sunday, a result that keeps Pep Guardiola's side lurking two points behind the leaders and ready to pounce.
After Saturday's 2-1 win at Chelsea - their 12th in 13 league matches - Aston Villa have claimed 18 points from losing positions so far this season, more than any other team.
Rodri only made return to competitive action in May after eight months out of action due to a ruptured anterior cruciate ligament.
Manchester United's Benjamin Sesko scoring a stoppage-time equaliser to deny 18th-placed West Ham United a 1-0 win.
Eberechi Eze timed his return to the Arsenal scoresheet to perfection with two goals in a 4-1 derby rout of Tottenham Hotspur.
Crystal Palace scored a stoppage-time winner to edge Liverpool 2-1 while Manchester United and Chelsea lost by an identical 3-1 margin in the English Premier League on Saturday.
Promoted Sunderland, who have defied expectations to stay in the top half of the Premier League table, could be the worst affected with six players going to the tournament, while the likes of Fulham, Manchester United, Burnley and Crystal Palace will also have to make do without some key personnel.
Diogo Jota, a Liverpool forward, and his younger brother Andre Silva were killed in a car accident in northwestern Spain on Thursday morning.
Aston Villa and Chelsea drop crucial points in the Premier League as Leeds and Burnley earn draws; James Milner sets appearance record.
A summary of Saturday's action in the Premier League.
Millwall and Montenegro goalkeeper Matija Sarkic died on Saturday at the age of 26, the Championship club confirmed.
Arsenal's Premier League title prospects were enhanced without them even kicking a ball on Wednesday as their closest challengers Manchester City and Aston Villa both dropped points.
It took 10 Premier League games for the first cracks to appear in Manchester City's facade last season, but Pep Guardiola got a much earlier reminder of his side's fall from grace on Saturday in another defeat to Tottenham Hotspur.
Brazil, who are fifth in the CONMEBOL table with 18 points from 12 games, host Colombia on March 21 and visit Argentina five days later in a match that could see Neymar come up against former Barcelona and Paris St Germain teammate Lionel Messi.
Arsenal maintained control of the Premier League title race as they chiselled out a nervy 2-1 win over London rivals Chelsea to open up a five-point lead at the top of the table on Sunday.
Forest's tally is the same number as Leicester City had accumulated by the same point of the 2015/16 campaign when they went on to become shock Premier League champions.
Arsenal re-established their five-point lead at the top of the Premier League with a 2-0 home win against Brentford on Wednesday and for the second evening running the goals flowed as Aston Villa won 4-3 in a thriller at Brighton and Hove Albion.
IMAGES from the Premier League matches played on Saturday.
The regional fire department of Castille-Leon, where Zamora is located, said on its website a car crashed shortly after midnight on Thursday and burst into flames, with two men, aged 28 and 26, found dead.
Chelsea battled from two goals down to beat West Ham 3-2 in the Premier League on Saturday with a stoppage-time Enzo Fernandez winner.
Second-string Liverpool were thumped 3-0 by Crystal Palace as Ismaila Sarr struck twice for the visitors in the League Cup on Wednesday, booking the London side's spot in the quarter-finals and piling more misery on Arne Slot's struggling side.
Manchester United manager Ruben Amorim would have enjoyed some relative calm during the international break after backing from club co-owner Jim Ratcliffe but will find himself in the Premier League maelstrom once again at Liverpool on Sunday.
Arsenal took a seven-point lead at the top of the Premier League after a scoreless draw with Nottingham Forest on Saturday.
The post was deleted about an hour later. The league did not immediately respond to a request for comment.
The game featured a minute's applause after the ninth minute for 34-year-old Hammers striker Michail Antonio, who is recovering in hospital following surgery on a fractured leg sustained in a car crash on Saturday.
Young becomes oldest Everton scorer in rout of Wolves
English champions and runners-up since the league restarted in the 1946-47 season after World War Two:
Arsenal maintained a searing pace at the top of the Premier League with a straightforward 2-0 win at Burnley, while Liverpool snapped a dreadful four-match losing run with a 2-0 victory over Aston Villa to climb provisionally to third.
Manchester City defender John Stones headed a controversial stoppage-time winner in a 2-1 victory at Wolverhampton Wanderers on Sunday that took them top of the Premier League and set a club record of 31 league games unbeaten.
IMAGES from the English Premier League matches played on Saturday.
A round-up of Saturday's action in the Premier League.
Manchester City's spending of more than 180 million pounds ($223.58 million) was the second-biggest outlay ever worldwide by a club in the January transfer window.
Brazil-born Nunes, 26, joined Premier League champions Manchester City from Wolverhampton Wanderers last season.
Images from Saturday's action in the Premier League.
